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KMID : 0355620110370010009
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Journal of Korean Association of Oral and Maxillofacial Surgeons
2011 Volume.37 No. 1 p.9 ~ p.14
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Oral cancer resection and reconstruction without blood transfusion by using recombinant human erythropoietin
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Kim Cheol-Whan
Lee Chung-Hyun
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Abstract
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Recently, the population of patients who refuse transfusion has increased for both religious and non-religious reasons, even in life threatening emergency situations. Their refusal has highlighted the need to develop nonblood transfusion surgery techniques to decrease the risk from blood transfusions.
A 57-year woman with an ulcerative lesion on the gingiva of the right upper molar area visited the department of oral and maxillofacial surgery in Dankook University Dental Hospital. After a preliminary evaluation, the patient was diagnosed with squamous cell carcinoma. As she refused blood transfusion during surgery for religious reasons, surgery was planned using recombinant human erythropoietin (rHuEPO) without a blood transfusion. The patient underwent a partial maxillectomy, supraomohyoid neck dissection, free radial forearm flap and split thickness skin graft under general anesthesia. rHuEPO and iron were used before and after surgery. The hemoglobin/hematocrit (Hb/Hct) level, iron (Fe) and total iron-binding capacity (TIBC) were assessed. The patient recovered completely without any blood transfusions. rHuEPO is a viable alternative for patients with religious objections to receiving blood transfusions.
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KEYWORD
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Recombinant erythropoietin, Blood transfusion, Mouth neoplasms
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